杨雅琴的老公:超难的啊！帮帮忙吧！

4.6 pregnant women and the breast-feeding period woman apply drugs: Once used the monkey to conduct the reproduction research, dosage reaching as high as person amount used 10 times, discovered this might send the miscarriage. This dosage in monkey's blood plasma peak density (Cmax) approximately manner 2 times. This in the animal confirmed by no means has sends is unbalanced the function. However, carries on by no means in the pregnant woman appropriately, has the good comparison research, therefore this uses in the pregnant woman not suitably. This whether passed through the milk secretion still to lack the material. When the young woman applies 200mg this, in the milk cannot pick out this medicine. However, because the research dosage is small, also this kind of medicine other varieties after the milk secretion, add it latent serious responded not good to the newborn and the babies and infants, the young woman should avoid applies this or in the application when stopping nursing.
4.7 driving machine, the vehicle, the ship, are engaged in the work high above the ground: Does not have the influence.
4.8 responded not good that,The (1). gastro-intestinal tract response is common, may display for the abdomen ill or the ache, the diarrhea, disgusting or the vomit. The (2). central nervous system responded may have dizzy, the headache, be addicted to rests or loses sleep. The (3). allergic reaction skin rash, the skin sao itch, the partner may have the leachability multi-red spot and blood vessel nervous dropsy. The minority patient has the photosensitized reaction. The (4). partner may occur: (1) epileptic paroxysm, the spirit exceptionally, are agitated restlessly, consciousness barrier, the illusion, tremble. (2) hematuria, gives off heat, the skin rash and so on nature nephritis displays. (3) phlebitis. (4) crystallization urine, sees in the high dose application when. (5) joint ache. The (5). minority patient may have the blood serum amino transferase ascension, the blood urea nitrogen markup and periphery the blood picture white blood cell reduces, is mildly, and assumes one.
4.9 medicines excessive: The mouse and big mouse Shan Ji takes orally this dosage to reach 4g/kg, has not discovered the lethal function. Acute medicine excessive when must carry on urges to spit or the gastric lavage urges the stomach evacuation, observes the condition change carefully, gives just right for the illness processing and the support therapy. Must maintain the suitable fluid infusion quantity.
5th, pharmacology characteristic
5.1 pharmacology toxicologies: This for the fluorine kui promise ketones antibiotics, has the broad spectrum resist bacteria function, especially to needs the oxygen leather blue negative bacillus resist bacteria activeness to be high, has the good resist bacteria function to the following bacterium in vitro: The intestines bacteriaceae majority of bacteria, including the citric acid pole bacteria, the sewer intestines bacillus, produce were mad intestines pole bacterias, large intestine Egypt and so on intestines bacillus hope the fungus, the gram Reber bacteria, the distortion bacteria, the monk bacteria, the will celebrate the bacteria, the vibrio, Ye you the woods fungus and so on. Outside the promise fluorine sand photostar to multiple bears the medicine fungus also to have the resist bacteria activeness. Bears the medicine to the penicillin gonorrhea napier Chinese zither fungus, flu bloodthirsty bacillus and the catarrh Morrah fungus also has the good resist bacteria function. Promise fluorine Sha Xingwei disinfectant, through function in bacterium DNA spiral enzyme A Asia unit, suppresses DNA the synthesis and the duplication causes the bacterium death.
5.2 medicine generation of dynamics: When empty stomach but takes orally the absorption rapidly not to be incomplete, approximately for gives the dose 30%~40%; Widely distributes in each organization, the body fluid, like liver, kidney, lung, prostate gland, testicle, womb and bile, sputamentum, Shui Paoye, blood, urine and so on, but has not seen in the central nervous system. The serum albumin union rate is 10%~15%, the blood eliminates Guan Shuaiqi (t1/2) is 3~4 hours, when the kidney function decrease may lengthen to 6~9 hours. Single oral administration this 400mg and 800mg, reach the peak value after 1~2 hour blood medicine density, blood medicine peak density (Cmax) respectively are 1.4~1.6mg/L and 2.5mg/L. The kidney (renal glomerulus has filtered and tubulus renalis secretion) and the courage system for the main excretion way, 26%~32% and is smaller than 10% by the primary form to discharge by the metabolite form from the urine in, and (or) the excrement discharges from the bile accounts for 28%~30%. Urine pH affects this solubility. When urine pH7.5 dissolves few, when other pH dissolves increases.
5.3 clinical front safety coefficient materials: